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Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

Multistep carcinogenesis involves more than six discrete events also important in normal development and cell behavior. Of these, local invasion and metastasis cause most cancer deaths but are the least well understood molecularly. We employed a combined in vitro/in vivo carcinogenesis model, that i...

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Bibliografski detalji
Glavni autori: Janda, Elzbieta, Lehmann, Kerstin, Killisch, Iris, Jechlinger, Martin, Herzig, Michaela, Downward, Julian, Beug, Hartmut, Grünert, Stefan
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199233/
https://ncbi.nlm.nih.gov/pubmed/11790801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109037
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