Autocrine PDGFR signaling promotes mammary cancer metastasis

Metastasis is the major cause of cancer morbidity, but strategies for direct interference with invasion processes are lacking. Dedifferentiated, late-stage tumor cells secrete multiple factors that represent attractive targets for therapeutic intervention. Here we show that metastatic potential of o...

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Detalhes bibliográficos
Main Authors: Jechlinger, Martin, Sommer, Andreas, Moriggl, Richard, Seither, Peter, Kraut, Norbert, Capodiecci, Paola, Donovan, Michael, Cordon-Cardo, Carlos, Beug, Hartmut, Grünert, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1469776/
https://ncbi.nlm.nih.gov/pubmed/16741576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24652
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