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Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

Multistep carcinogenesis involves more than six discrete events also important in normal development and cell behavior. Of these, local invasion and metastasis cause most cancer deaths but are the least well understood molecularly. We employed a combined in vitro/in vivo carcinogenesis model, that i...

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Main Authors: Janda, Elzbieta, Lehmann, Kerstin, Killisch, Iris, Jechlinger, Martin, Herzig, Michaela, Downward, Julian, Beug, Hartmut, Grünert, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199233/
https://ncbi.nlm.nih.gov/pubmed/11790801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109037
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