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Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

Multistep carcinogenesis involves more than six discrete events also important in normal development and cell behavior. Of these, local invasion and metastasis cause most cancer deaths but are the least well understood molecularly. We employed a combined in vitro/in vivo carcinogenesis model, that i...

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Detalhes bibliográficos
Main Authors: Janda, Elzbieta, Lehmann, Kerstin, Killisch, Iris, Jechlinger, Martin, Herzig, Michaela, Downward, Julian, Beug, Hartmut, Grünert, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199233/
https://ncbi.nlm.nih.gov/pubmed/11790801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109037
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