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Lineage Commitment in the Thymus: Only the Most Differentiated (TCR(hi)bcl-2(hi)) Subset of CD4(+)CD8(+)Thymocytes Has Selectively Terminated CD4 or CD8 Synthesis

Lineage commitment is a developmental process by which individual CD4(+)CD8(+) (double positive, DP) thymocytes make a decision to differentiate into either CD4(+) or CD8(+) T cells. However, the molecular event(s) that defines lineage commitment is controversial. We have previously proposed that li...

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Sonraí Bibleagrafaíochta
Main Authors: Punt, Jennifer A., Suzuki, Harumi, Granger, Larry G., Sharrow, Susan O., Singer, Alfred
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 1996
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196385/
https://ncbi.nlm.nih.gov/pubmed/8976166
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