The organotin-induced thymus atrophy, characterized by depletion of CD4+ CD8+ thymocytes, is preceded by a reduction of the immature CD4- CD8+ TcR alpha beta-/low CD2high thymoblast subset.

Lignende værker

• Recovery from chemically induced thymus atrophy starts with CD4- CD8- CD2high TcR alpha beta-/low thymocytes and results in an increased formation of CD4- CD8- TcR alpha beta high thymocytes.
  af: Pieters, R H, et al.
  Udgivet: (1993)
• Selective inhibition of immature CD4-CD8+ thymocyte proliferation, but not differentiation, by the thymus atrophy-inducing compound di-n-butyltin dichloride.
  af: Pieters, R H, et al.
  Udgivet: (1994)
• T Cell Receptor (TCR)-induced Death of Immature CD4(+)CD8(+) Thymocytes by Two Distinct Mechanisms Differing in Their Requirement for CD28 Costimulation: Implications for Negative Selection in the Thymus
  af: Punt, Jennifer A., et al.
  Udgivet: (1997)
• Murine T-Lymphomas Corresponding to the Immature CD4(-)8(+) Thymocyte Subset
  af: Richie, Ellen R., et al.
  Udgivet: (1991)
• Commitment of Immature CD4(+)8(+) Thymocytes to the CD4 Lineage Requires CD3 Signaling but Does Not Require Expression of Clonotypic T Cell Receptor (TCR) Chains
  af: Suzuki, Harumi, et al.
  Udgivet: (1997)