Yüklüyor......
Duplex DNA catalyzes the chemical rearrangement of a malondialdehyde deoxyguanosine adduct
The primary DNA lesion induced by malondialdehyde, a byproduct of lipid peroxidation and prostaglandin synthesis, is 3-(2′-deoxy-β-d-erythro-pentofuranosyl)-pyrimido[1,2-a]purin-10(3H)-one (M(1)G). When placed opposite cytosine (underlined) at neutral pH in either the d(GGTMTCCG)⋅d(CGGACACC) or d(AT...
Kaydedildi:
| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The National Academy of Sciences
1999
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21963/ https://ncbi.nlm.nih.gov/pubmed/10359760 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|