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Efficient Generation of a Hepatitis B Virus Cytotoxic T Lymphocyte Epitope Requires the Structural Features of Immunoproteasomes

Interferon (IFN)-γ–induced cells express the proteasome subunits low molecular weight protein (LMP)2, LMP7, and MECL-1 (multicatalytic endopeptidase complex–like 1), leading to the formation of immunoproteasomes. Although these subunits are thought to optimize MHC class I antigen processing, the ext...

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Detalhes bibliográficos
Main Authors: Sijts, Alice J.A.M., Ruppert, Thomas, Rehermann, Barbara, Schmidt, Marion, Koszinowski, Ulrich, Kloetzel, Peter-M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195811/
https://ncbi.nlm.nih.gov/pubmed/10662796
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