Three Immunoproteasome-Associated Subunits Cooperatively Generate a Cytotoxic T-Lymphocyte Epitope of Epstein-Barr Virus LMP2A by Overcoming Specific Structures Resistant to Epitope Liberation

The precise roles of gamma interferon-inducible immunoproteasome-associated molecules in generation of cytotoxic T-lymphocyte (CTL) epitopes have yet to be fully elucidated. We describe here a unique epitope derived from the Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A) presented by HL...

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Detalhes bibliográficos
Main Authors: Ito, Yoshinori, Kondo, Eisei, Demachi-Okamura, Ayako, Akatsuka, Yoshiki, Tsujimura, Kunio, Tanimoto, Mitsune, Morishima, Yasuo, Takahashi, Toshitada, Kuzushima, Kiyotaka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346843/
https://ncbi.nlm.nih.gov/pubmed/16378990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.883-890.2006
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