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Autophagy Creates a CTL Epitope That Mimics Tumor-Associated Antigens

The detailed mechanisms responsible for processing tumor-associated antigens and presenting them to CTLs remain to be fully elucidated. In this study, we demonstrate a unique CTL epitope generated from the ubiquitous protein puromycin-sensitive aminopeptidase, which is presented via HLA-A24 on leuke...

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Detalhes bibliográficos
Main Authors: Demachi-Okamura, Ayako, Torikai, Hiroki, Akatsuka, Yoshiki, Miyoshi, Hiroyuki, Yoshimori, Tamotsu, Kuzushima, Kiyotaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469533/
https://ncbi.nlm.nih.gov/pubmed/23071732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047126
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