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Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection

IFN-γ is known as the initial and primary inducer of immunoproteasomes during viral infections. We now report that type I IFN induced the transcription and translation of immunoproteasome subunits, their incorporation into the proteasome complex, and the generation of an immunoproteasome-dependent C...

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Detalhes bibliográficos
Main Authors: Shin, Eui-Cheol, Seifert, Ulrike, Kato, Takanobu, Rice, Charles M., Feinstone, Stephen M., Kloetzel, Peter-M., Rehermann, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592549/
https://ncbi.nlm.nih.gov/pubmed/17039255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29832
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