Delayed Induction, Not Impaired Recruitment of Specific CD8+ T Cells, Causes the Late Onset of Acute Hepatitis C

BACKGROUND & AIMS: Hepatitis C virus (HCV) infection is characterized by lack of immune-mediated liver injury despite a high level of HCV replication during the incubation phase, which lasts about 8 weeks. We investigated whether this results from delayed recruitment of HCV-specific T cells and...

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Main Authors: Shin, Eui-Cheol, Park, Su-Hyung, DeMino, Mary, Nascimbeni, Michelina, Mihalik, Kathleen, Major, Marian, Veerapu, Naga S., Heller, Theo, Feinstone, Stephen M., Rice, Charles M., Rehermann, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359650/
https://ncbi.nlm.nih.gov/pubmed/21699897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.05.006
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