Kinetics of CD4(+) and CD8(+) Memory T-Cell Responses during Hepatitis C Virus Rechallenge of Previously Recovered Chimpanzees

The immunological correlates of hepatitis C virus (HCV)-specific immunity are not well understood. Antibodies to HCV structural proteins do not appear to play a key role in clearance of the virus and do not persist after recovery. Here, we studied the kinetics of the cellular immune responses of thr...

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Detalhes bibliográficos
Main Authors: Nascimbeni, Michelina, Mizukoshi, Eishiro, Bosmann, Markus, Major, Marian E., Mihalik, Kathleen, Rice, Charles M., Feinstone, Stephen M., Rehermann, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152131/
https://ncbi.nlm.nih.gov/pubmed/12663785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4781-4793.2003
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