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Differential Influence on Cytotoxic T Lymphocyte Epitope Presentation by Controlled Expression of Either Proteasome Immunosubunits or Pa28

The proteasome is the principal provider of major histocompatibility complex (MHC) class I–presented peptides. Interferon (IFN)-γ induces expression of three catalytically active proteasome subunits (LMP2, LMP7, and MECL-1) and the proteasome-associated activator PA28. These molecules are thought to...

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Bibliografiske detaljer
Main Authors: van Hall, Thorbald, Sijts, Alice, Camps, Marcel, Offringa, Rienk, Melief, Cornelis, Kloetzel, Peter-M., Ossendorp, Ferry
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193234/
https://ncbi.nlm.nih.gov/pubmed/10952718
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