Efficient Identification of Novel Hla-A*0201–Presented Cytotoxic T Lymphocyte Epitopes in the Widely Expressed Tumor Antigen Prame by Proteasome-Mediated Digestion Analysis

We report the efficient identification of four human histocompatibility leukocyte antigen (HLA)-A*0201–presented cytotoxic T lymphocyte (CTL) epitopes in the tumor-associated antigen PRAME using an improved “reverse immunology” strategy. Next to motif-based HLA-A*0201 binding prediction and actual b...

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Main Authors: Kessler, Jan H., Beekman, Nico J., Bres-Vloemans, Sandra A., Verdijk, Pauline, van Veelen, Peter A., Kloosterman-Joosten, Antoinette M., Vissers, Debby C.J., ten Bosch, George J.A., Kester, Michel G.D., Sijts, Alice, Drijfhout, Jan Wouter, Ossendorp, Ferry, Offringa, Rienk, Melief, Cornelis J.M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195886/
https://ncbi.nlm.nih.gov/pubmed/11136822
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