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Proteasome immunosubunits protect against the development of CD8 T-cell-mediated autoimmune diseases
Exposure of cells to inflammatory cytokines induces the expression of three proteasome immunosubunits, two of which are encoded in the MHC-II region. The induced subunits replace their constitutive homologues in newly formed, so called immunoproteasomes. Immunosubunit incorporation enhances the prot...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159700/ https://ncbi.nlm.nih.gov/pubmed/21804012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101003 |
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