Human RNA polymerase II is partially blocked by DNA adducts derived from tumorigenic benzo[c]phenanthrene diol epoxides: relating biological consequences to conformational preferences

Eitemau Tebyg

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• CONFORMATIONAL SEARCHES ELUCIDATE EFFECTS OF STEREOCHEMISTRY ON STRUCTURES OF DEOXYADENOSINE COVALENTLY BOUND TO TUMORIGENIC METABOLITES OF BENZO[C] PHENANTHRENE
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  Cyhoeddwyd: (2004)
• Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase ι
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• Structure of DNA polymerase β with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features
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• Nucleotide incorporation by human DNA polymerase γ opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine
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  Cyhoeddwyd: (2004)