Impaired V(D)J Recombination and Lymphocyte Development in Core RAG1-expressing Mice

RAG1 and RAG2 are the lymphocyte-specific components of the V(D)J recombinase. In vitro analyses of RAG function have relied on soluble, highly truncated “core” RAG proteins. To identify potential functions for noncore regions and assess functionality of core RAG1 in vivo, we generated core RAG1 kno...

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Detaylı Bibliyografya
Asıl Yazarlar: Dudley, Darryll D., Sekiguchi, JoAnn, Zhu, Chengming, Sadofsky, Moshe J., Whitlow, Scott, DeVido, Jeffrey, Monroe, Robert J., Bassing, Craig H., Alt, Frederick W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2003
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194253/
https://ncbi.nlm.nih.gov/pubmed/14581608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030627
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