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Impaired V(D)J Recombination and Lymphocyte Development in Core RAG1-expressing Mice
RAG1 and RAG2 are the lymphocyte-specific components of the V(D)J recombinase. In vitro analyses of RAG function have relied on soluble, highly truncated “core” RAG proteins. To identify potential functions for noncore regions and assess functionality of core RAG1 in vivo, we generated core RAG1 kno...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194253/ https://ncbi.nlm.nih.gov/pubmed/14581608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030627 |
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