Impaired V(D)J Recombination and Lymphocyte Development in Core RAG1-expressing Mice

RAG1 and RAG2 are the lymphocyte-specific components of the V(D)J recombinase. In vitro analyses of RAG function have relied on soluble, highly truncated “core” RAG proteins. To identify potential functions for noncore regions and assess functionality of core RAG1 in vivo, we generated core RAG1 kno...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dudley, Darryll D., Sekiguchi, JoAnn, Zhu, Chengming, Sadofsky, Moshe J., Whitlow, Scott, DeVido, Jeffrey, Monroe, Robert J., Bassing, Craig H., Alt, Frederick W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2003
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194253/
https://ncbi.nlm.nih.gov/pubmed/14581608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030627
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia