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Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice

RAG1 and RAG2 play a central role in V(D)J recombination, a process for antigen receptor gene assembly. The truncated ‘core’ regions of RAGs are sufficient to catalyze the recombination reaction, although with lower joining efficiency than full-length proteins. To investigate the role of the non-cor...

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Bibliografski detalji
Glavni autori: Talukder, Sadiqur R., Dudley, Darryll D., Alt, Frederick W., Takahama, Yousuke, Akamatsu, Yoshiko
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC516053/
https://ncbi.nlm.nih.gov/pubmed/15328366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh778
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