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Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice
RAG1 and RAG2 play a central role in V(D)J recombination, a process for antigen receptor gene assembly. The truncated ‘core’ regions of RAGs are sufficient to catalyze the recombination reaction, although with lower joining efficiency than full-length proteins. To investigate the role of the non-cor...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516053/ https://ncbi.nlm.nih.gov/pubmed/15328366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh778 |
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