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Proteolytic Processing of Stat6 Signaling in Mast Cells as a Negative Regulatory Mechanism
Accumulating evidence has shown the importance of Stat6-mediated signaling in allergic diseases. In this study, we show a novel regulatory mechanism of Stat6-mediated signaling in mast cells. When Stat6 is activated by interleukin (IL)-4 and translocated to the nucleus, Stat6 is cleaved by a nucleus...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194019/ https://ncbi.nlm.nih.gov/pubmed/12093868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011682 |
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