IL-4–Stat6 Signaling Induces Tristetraprolin Expression and Inhibits TNF-α Production in Mast Cells

Increasing evidence has revealed that mast cell–derived tumor necrosis factor α (TNF-α) plays a critical role in a number of inflammatory responses by recruiting inflammatory leukocytes. In this paper, we investigated the regulatory role of interleukin 4 (IL-4) in TNF-α production in mast cells. IL-...

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Detalhes bibliográficos
Main Authors: Suzuki, Kotaro, Nakajima, Hiroshi, Ikeda, Kei, Maezawa, Yuko, Suto, Akira, Takatori, Hiroaki, Saito, Yasushi, Iwamoto, Itsuo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194141/
https://ncbi.nlm.nih.gov/pubmed/14638848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031701
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