RNA-Binding Protein ZFP36L2 Downregulates Helios Expression and Suppresses the Function of Regulatory T Cells

The zinc finger protein 36-like 2, ZFP36L2, is a member of a small family of RNA-binding proteins composed by ZFP36 (also known as tristetraprolin, TTP), ZFP36L1 and ZFP36L2 in humans, with corresponding murine orthologs. These proteins bind to adenine uridine-rich element (ARE) in the 3′untranslate...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Makita, Sohei, Takatori, Hiroaki, Iwata, Arifumi, Tanaka, Shigeru, Furuta, Shunsuke, Ikeda, Kei, Suto, Akira, Suzuki, Kotaro, Ramos, Silvia B. V., Nakajima, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324482/
https://ncbi.nlm.nih.gov/pubmed/32655569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01291
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