ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK–RSK pathway

Low-density lipoprotein receptor (LDLR) mRNA is unstable, but is stabilized upon extracellular signal-regulated kinase (ERK) activation, possibly through the binding of certain proteins to the LDLR mRNA 3′-untranslated region (UTR), although the detailed mechanism underlying this stability control i...

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Bibliographische Detailangaben
Hauptverfasser: Adachi, Shungo, Homoto, Masae, Tanaka, Rikou, Hioki, Yusaku, Murakami, Hiroshi, Suga, Hiroaki, Matsumoto, Masaki, Nakayama, Keiichi I., Hatta, Tomohisa, Iemura, Shun-ichiro, Natsume, Tohru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150769/
https://ncbi.nlm.nih.gov/pubmed/25106868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku652
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