Development of Autoimmune Hepatitis-like Disease and Autoantibody Production to Nuclear Antigens in Mice Lacking B and T Lymphocyte Attenuator (BTLA)

OBJECTIVE: B and T lymphocyte attenuator (BTLA), a coreceptor expressed on lymphocytes, has recently been described as an inhibitory coreceptor that negatively regulates lymphocyte activation. The purpose of this study was to investigate the role of BTLA in the regulation of immune homeostasis and t...

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Hauptverfasser: Oya, Yoshihiro, Watanabe, Norihiko, Owada, Takayoshi, Oki, Mie, Hirose, Koichi, Suto, Akira, Kagami, Shin-ichiro, Nakajima, Hiroshi, Kishimoto, Takashi, Iwamoto, Itsuo, Murphy, Theresa L, Murphy, Kenneth M, Saito, Yasushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782777/
https://ncbi.nlm.nih.gov/pubmed/18668554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23674
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