Development of Autoimmune Hepatitis-like Disease and Autoantibody Production to Nuclear Antigens in Mice Lacking B and T Lymphocyte Attenuator (BTLA)

OBJECTIVE: B and T lymphocyte attenuator (BTLA), a coreceptor expressed on lymphocytes, has recently been described as an inhibitory coreceptor that negatively regulates lymphocyte activation. The purpose of this study was to investigate the role of BTLA in the regulation of immune homeostasis and t...

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Detalhes bibliográficos
Main Authors: Oya, Yoshihiro, Watanabe, Norihiko, Owada, Takayoshi, Oki, Mie, Hirose, Koichi, Suto, Akira, Kagami, Shin-ichiro, Nakajima, Hiroshi, Kishimoto, Takashi, Iwamoto, Itsuo, Murphy, Theresa L, Murphy, Kenneth M, Saito, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782777/
https://ncbi.nlm.nih.gov/pubmed/18668554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23674
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