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Constitutive Expression of AID Leads to Tumorigenesis
Genome stability is regulated by the balance between efficiencies of the repair machinery and genetic alterations such as mutations and chromosomal rearrangements. It has been postulated that deregulation of class switch recombination (CSR) and somatic hypermutation (SHM), which modify the immunoglo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193972/ https://ncbi.nlm.nih.gov/pubmed/12732658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030275 |
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