AID to overcome the limitations of genomic information by introducing somatic DNA alterations

The immune system has adopted somatic DNA alterations to overcome the limitations of the genomic information. Activation induced cytidine deaminase (AID) is an essential enzyme to regulate class switch recombination (CSR), somatic hypermutation (SHM) and gene conversion (GC) of the immunoglobulin ge...

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書目詳細資料
發表在:Proc Jpn Acad Ser B Phys Biol Sci
Main Authors: Honjo, Tasuku, Muramatsu, Masamichi, Nagaoka, Hitoshi, Kinoshita, Kazuo, Shinkura, Reiko
格式: Artigo
語言:Inglês
出版: The Japan Academy 2006
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323042/
https://ncbi.nlm.nih.gov/pubmed/25873751
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