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AID to overcome the limitations of genomic information by introducing somatic DNA alterations
The immune system has adopted somatic DNA alterations to overcome the limitations of the genomic information. Activation induced cytidine deaminase (AID) is an essential enzyme to regulate class switch recombination (CSR), somatic hypermutation (SHM) and gene conversion (GC) of the immunoglobulin ge...
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| Udgivet i: | Proc Jpn Acad Ser B Phys Biol Sci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Japan Academy
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4323042/ https://ncbi.nlm.nih.gov/pubmed/25873751 |
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