AID to overcome the limitations of genomic information by introducing somatic DNA alterations

Lignende værker

• Activation-induced Deaminase (AID)-directed Hypermutation in the Immunoglobulin Sμ Region: Implication of AID Involvement in a Common Step of Class Switch Recombination and Somatic Hypermutation
  af: Nagaoka, Hitoshi, et al.
  Udgivet: (2002)
• De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination
  af: Begum, Nasim A., et al.
  Udgivet: (2004)
• AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
  af: Kobayashi, Maki, et al.
  Udgivet: (2009)
• DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase
  af: Nagaoka, Hitoshi, et al.
  Udgivet: (2005)
• RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
  af: Eto, Tomonori, et al.
  Udgivet: (2003)