A limited role for microglia in antibody mediated plaque clearance in APP mice

Amyloid-β (Aβ) accumulation in senile plaques is a hallmark of Alzheimer’s disease (AD). Immunotherapy is a leading approach for amyloid clearance, despite the early termination of the Elan clinical trial with active immunization due to a few cases of meningoencephalitis. The mechanisms of immunothe...

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Detaylı Bibliyografya
Asıl Yazarlar: Garcia-Alloza, Monica, Dodwell, Sarah A., Ferrara, Brian J., Hickey, Gregory A., Hyman, Bradley T., Bacskai, Brian J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193669/
https://ncbi.nlm.nih.gov/pubmed/17822910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.07.019
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