Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that causes parkinsonism in humans and nonhuman animals, and its use has led to greater understanding of the pathogenesis of Parkinson’s disease. However, its molecular targets have not been defined. We show that mice lacking the ge...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mandir, Allen S., Przedborski, Serge, Jackson-Lewis, Vernice, Wang, Zhao-Qi, Simbulan-Rosenthal, Cynthia M., Smulson, Mark E., Hoffman, Brian E., Guastella, Daniel B., Dawson, Valina L., Dawson, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21936/
https://ncbi.nlm.nih.gov/pubmed/10318960
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados