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Restrictions Limiting the Generation of DNA Double Strand Breaks during Chromosomal V(D)J Recombination
Antigen receptor loci are composed of numerous variable (V), diversity (D), and joining (J) gene segments, each flanked by recombination signal sequences (RSSs). The V(D)J recombination reaction proceeds through RSS recognition and DNA cleavage steps making it possible for multiple DNA double strand...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193590/ https://ncbi.nlm.nih.gov/pubmed/11828005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011803 |
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