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CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms
CRISPR–Cas9–based genome editing has transformed the life sciences, enabling virtually unlimited genetic manipulation of genomes: The RNA-guided Cas9 endonuclease cuts DNA at a specific target sequence and the resulting double-strand breaks are mended by one of the intrinsic cellular repair pathways...
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| Veröffentlicht in: | Life Sci Alliance |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Life Science Alliance LLC
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587125/ https://ncbi.nlm.nih.gov/pubmed/31196871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800267 |
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