Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8(+) T Cells

Transgenic (TG) mice expressing a high copy number of interleukin (IL)-7 cDNA under the control of the major histocomaptability complex (MHC) class II promoter display a 10–20-fold increase in total T cell numbers. Here, we show that the increase in T cell numbers in IL-7 TG mice is most apparent at...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kieper, William C., Tan, Joyce T., Bondi-Boyd, Brea, Gapin, Laurent, Sprent, Jonathan, Ceredig, Rhodri, Surh, Charles D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193553/
https://ncbi.nlm.nih.gov/pubmed/12070281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020067
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados