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Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8(+) T Cells

Previous work has shown that memory-phenotype CD44(hi) CD8(+) cells are controlled by a cytokine, interleukin (IL)-15. However, the dependency of CD44(hi) CD8(+) cells on IL-15 is partial rather than complete. Here, evidence is presented that CD44(hi) CD8(+) cells comprise a mixed population of IL-1...

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Autori principali: Judge, Adam D., Zhang, Xiaohong, Fujii, Hideki, Surh, Charles D., Sprent, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194030/
https://ncbi.nlm.nih.gov/pubmed/12370255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020772
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