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Aging Leads to Disturbed Homeostasis of Memory Phenotype CD8(+) Cells
Examining the rate of in vivo T cell turnover (proliferation) in aged mice revealed a marked reduction in turnover at the level of memory-phenotype CD44(hi) CD8(+) cells relative to young mice. Based on adoptive transfer experiments, the reduced turnover of aged CD44(hi) CD8(+) cells reflected an in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193587/ https://ncbi.nlm.nih.gov/pubmed/11828003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011267 |
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