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Normal T cell homeostasis: the conversion of naïve cells into memory-phenotype cells
Covert TCR signals from contact with self-ligands synergize with IL-7-induced anti-apoptotic signals to promote survival of naïve T cells in a resting state. The level of background TCR signaling in naïve T cells is set by post-thymic TCR tuning and operates at an intensity just below that required...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434123/ https://ncbi.nlm.nih.gov/pubmed/21739670 |
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