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Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8(+) T Cells
Transgenic (TG) mice expressing a high copy number of interleukin (IL)-7 cDNA under the control of the major histocomaptability complex (MHC) class II promoter display a 10–20-fold increase in total T cell numbers. Here, we show that the increase in T cell numbers in IL-7 TG mice is most apparent at...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193553/ https://ncbi.nlm.nih.gov/pubmed/12070281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020067 |
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