Hyperactivation of P21(ras) and the Hematopoietic-Specific Rho Gtpase, Rac2, Cooperate to Alter the Proliferation of Neurofibromin-Deficient Mast Cells in Vivo and in Vitro

Mutations in the NF1 tumor suppressor gene cause neurofibromatosis type I (NF1), a disease characterized by the formation of cutaneous neurofibromas infiltrated with a high density of degranulating mast cells. A hallmark of cell lines generated from NF1 patients or Nf1-deficient mice is their propen...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ingram, David A., Hiatt, Kelly, King, Alastair J., Fisher, Lucy, Shivakumar, Rama, Derstine, Christina, Wenning, Mary Jo, Diaz, Bruce, Travers, Jeffrey B., Hood, Antoinette, Marshall, Mark, Williams, David A., Clapp, D. Wade
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2001
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193446/
https://ncbi.nlm.nih.gov/pubmed/11435472
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky