Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line: A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling

Somatic cell mutagenesis is a powerful tool for characterizing receptor systems. We reported previously two complementation groups of mutant cell lines derived from CD14-transfected Chinese hamster ovary–K1 fibroblasts defective in responses to bacterial endotoxin. Both classes of mutants expressed...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schromm, Andra B., Lien, Egil, Henneke, Philipp, Chow, Jesse C., Yoshimura, Atsutoshi, Heine, Holger, Latz, Eicke, Monks, Brian G., Schwartz, David A., Miyake, Kensuke, Golenbock, Douglas T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193443/
https://ncbi.nlm.nih.gov/pubmed/11435474
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados