Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice

Chemokine receptors transduce signals important for the function and trafficking of leukocytes. Recently, it has been shown that CC chemokine receptor (CCR)8 is selectively expressed by Th2 subsets, but its functional relevance is unclear. To address the biological role of CCR8, we generated CCR8 de...

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Main Authors: Chensue, Stephen W., Lukacs, Nicholas W., Yang, Tong-Yuan, Shang, Xiaozhou, Frait, Kirsten A., Kunkel, Steven L., Kung, Ted, Wiekowski, Maria T., Hedrick, Joseph A., Cook, Donald N., Zingoni, Alessandra, Narula, Satwant K., Zlotnik, Albert, Barrat, Franck J., O'Garra, Anne, Napolitano, Monica, Lira, Sergio A.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193397/
https://ncbi.nlm.nih.gov/pubmed/11238588
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