Transgenic Expression of the Chemokine Receptor Encoded by Human Herpesvirus 8 Induces an Angioproliferative Disease Resembling Kaposi's Sarcoma

Human herpesvirus 8 (HHV8, also known as Kaposi's sarcoma [KS]-associated herpesvirus) has been implicated as an etiologic agent for KS, an angiogenic tumor composed of endothelial, inflammatory, and spindle cells. Here, we report that transgenic mice expressing the HHV8-encoded chemokine recep...

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Autori principali: Yang, Tong-Yuan, Chen, Shu-Cheng, Leach, Michael W., Manfra, Denise, Homey, Bernhard, Wiekowski, Maria, Sullivan, Lee, Jenh, Chung-Her, Narula, Satwant K., Chensue, Stephen W., Lira, Sergio A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195818/
https://ncbi.nlm.nih.gov/pubmed/10662790
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