Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice

Chemokine receptors transduce signals important for the function and trafficking of leukocytes. Recently, it has been shown that CC chemokine receptor (CCR)8 is selectively expressed by Th2 subsets, but its functional relevance is unclear. To address the biological role of CCR8, we generated CCR8 de...

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Hlavní autoři: Chensue, Stephen W., Lukacs, Nicholas W., Yang, Tong-Yuan, Shang, Xiaozhou, Frait, Kirsten A., Kunkel, Steven L., Kung, Ted, Wiekowski, Maria T., Hedrick, Joseph A., Cook, Donald N., Zingoni, Alessandra, Narula, Satwant K., Zlotnik, Albert, Barrat, Franck J., O'Garra, Anne, Napolitano, Monica, Lira, Sergio A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2001
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193397/
https://ncbi.nlm.nih.gov/pubmed/11238588
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