Chemokine Receptor 1 Knockout Abrogates Natural Killer Cell Recruitment and Impairs Type-1 Cytokines in Lymphoid Tissue during Pulmonary Granuloma Formation

Mice with targeted mutation of chemokine receptor 1 (CCR1) were used to assess the contribution of CCR1 agonists to local, regional, and systemic inflammatory-related events during experimental pulmonary granuloma formation. Models of Th1 (type-1) and Th2 (type-2) cell-mediated lung granulomas were...

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Autori principali: Shang, Xiaozhou, Qiu, Boqin, Frait, Kirsten A., Hu, Jerry S., Sonstein, Joanne, Curtis, Jeffrey L., Lu, Bao, Gerard, Craig, Chensue, Stephen W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885763/
https://ncbi.nlm.nih.gov/pubmed/11106578
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