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Effect of C-C Chemokine Receptor 2 (CCR2) Knockout on Type-2 (Schistosomal Antigen-Elicited) Pulmonary Granuloma Formation : Analysis of Cellular Recruitment and Cytokine Responses

Monocyte chemotactic protein (MCP)-1 is postulated to play a role in cellular recruitment during inflammatory reactions. C-C chemokine receptor 2 (CCR2) is considered the major G-protein coupled receptor for MCP-1/JE. We reported that mice with knockout of the CCR2 gene display partially impaired ty...

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Autores principales: Warmington, Kelly S., Boring, Landin, Ruth, Jeffrey H., Sonstein, Joanne, Hogaboam, Cory M., Curtis, Jeffrey L., Kunkel, Steven L., Charo, Israel R., Chensue, Stephen W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866581/
https://ncbi.nlm.nih.gov/pubmed/10329593
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