Short Telomeres Result in Organismal Hypersensitivity to Ionizing Radiation in Mammals

Here we show a correlation between telomere length and organismal sensitivity to ionizing radiation (IR) in mammals. In particular, fifth generation (G5) mouse telomerase RNA (mTR)(−/)− mice, with telomeres 40% shorter than in wild-type mice, are hypersensitive to cumulative doses of gamma rays. 60%...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Goytisolo, Fermín A., Samper, Enrique, Martín-Caballero, Juan, Finnon, Paul, Herrera, Eloísa, Flores, Juana M., Bouffler, Simon D., Blasco, María A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2000
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193093/
https://ncbi.nlm.nih.gov/pubmed/11104804
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller