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Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeres
Mismatch repair (MMR) has important roles in meiotic and mitotic recombination, DNA damage signaling, and various aspects of DNA metabolism including class-switch recombination, somatic hypermutation, and triplet-repeat expansion. Defects in MMR are responsible for human cancers characterized by mic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950861/ https://ncbi.nlm.nih.gov/pubmed/17785530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.430107 |
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