Thioredoxin, a Redox Enzyme Released in Infection and Inflammation, Is a Unique Chemoattractant for Neutrophils, Monocytes, and T Cells

Thioredoxin (Trx) is a ubiquitous intracellular protein disulfide oxidoreductase with a CXXC active site that can be released by various cell types upon activation. We show here that Trx is chemotactic for monocytes, polymorphonuclear leukocytes, and T lymphocytes, both in vitro in the standard micr...

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Main Authors: Bertini, Riccardo, Zack Howard, O.M., Dong, Hui-Fang, Oppenheim, Joost J., Bizzarri, Cinzia, Sergi, Rita, Caselli, Gianfranco, Pagliei, Sabrina, Romines, Brie, Wilshire, Jennifer A., Mengozzi, Manuela, Nakamura, Hajime, Yodoi, Junji, Pekkari, Klas, Gurunath, Ramanathan, Holmgren, Arne, Herzenberg, Leonore A., Herzenberg, Leonard A., Ghezzi, Pietro
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1999
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193090/
https://ncbi.nlm.nih.gov/pubmed/10359582
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