Chronic elevation of plasma thioredoxin: Inhibition of chemotaxis and curtailment of life expectancy in AIDS

Thioredoxin (Trx) is an intracellular redox protein with extracellular cytokine-like and chemokine-like activities. We show here that, although plasma Trx levels are unrelated to survival of HIV-infected individuals with CD4 cell counts above 200/μl blood, survival is significantly impaired (P = 0.0...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Nakamura, Hajime, De Rosa, Stephen C., Yodoi, Junji, Holmgren, Arne, Ghezzi, Pietro, Herzenberg, Leonard A., Herzenberg, Leonore A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041624998
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