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CD4(+) T cells derived from B cell-deficient mice inhibit the establishment of peripheral B cell pools

We demonstrate that adoptive transfer of peritoneal cavity B cells fails to replenish the peripheral B-1 cells in adult B cell-deficient (μ(−/−)) mice but does replenish adult RAG-1(−/−) mice. We show that this lack of self-replenishment in μ(−/−) mice is mediated by strongly inhibitory, radiation-s...

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Detalhes bibliográficos
Main Authors: Baumgarth, Nicole, Jager, Gina C., Herman, Ometa C., Herzenberg, Leonard A., Herzenberg, Leonore A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18307/
https://ncbi.nlm.nih.gov/pubmed/10781082
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