Predominant V(H) genes expressed in innate antibodies are associated with distinctive antigen-binding sites

Antibodies to phosphatidylcholine (PtC), a common constituent of mammalian and bacterial cell membranes, represent a large proportion of the natural antibody repertoire in mice. Previous studies of several mouse strains (e.g., C57BL/6) have shown that anti-PtC antibodies are mainly encoded by the V(...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Seidl, Katherine J., Wilshire, Jennifer A., MacKenzie, John D., Kantor, Aaron B., Herzenberg, Leonard A., Herzenberg, Leonore A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2262
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